Estimation of the Level of Oxidative Factors and Some Biochemical Parameters that Affect Renal Disease

Zahra'a Hamza

doi:10.37899/journallalifesci.v7i3.5903

Zahra'a Hamza Al-Furat AL-Awsat Technical University/ Department of Anesthesia Techniques, Iraq

DOI: https://doi.org/10.37899/journallalifesci.v7i3.5903

Keywords: Renal Failure, Hemodialysis, Oxidative Stress, Biochemical Parameters, Glutathione

Abstract

The kidneys are crucial organs with a bean-like form that can be found on either side of the spine and filter toxins and excess water from the blood. Similar to other organs in the body, the kidneys are susceptible to injury due to a variety of conditions. The current study included a hundred individuals on dialysis who were suffering from renal failure. Their ages ranged from 16 to 70 years old. These patients were enrolled in Al-Sadder Medical City in the governorate of Al-Najaf Al-Ashraf. The same precautions were also taken on the healthy group, which consisted of fifty samples whose ages were roughly equal to those of the dialysis patients. These healthy samples were kept in test tubes designated for this purpose and were kept at the proper temperature until the required number of samples was completed. According to the current study's outcomes, dialysis patients had significantly higher levels of oxidative factors, urea, creatinine, and glucose than did the control group. Creatinine, Urea, Uric Acid, Fe, and Ferritin levels were higher in patients than in the control group, but D3 and HGB levels were significantly lower. Due to patients' impaired kidney function, the immune response is to blame for this. Regarding GSH, there is no appreciable distinction between the sick group and the healthy group. The patients' participation in some treatments is said to be the cause.

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