The Determinant Factors of Preeclampsia Incidence in Pregnant Women at Haji Hospital Makassar in 2024
Abstract
Hypertensive disorders during pregnancy, particularly preeclampsia, are a leading cause of maternal and perinatal mortality worldwide. Preeclampsia can progress into severe complications such as eclampsia and HELLP syndrome. Factors such as age, pregnancy history, and body mass index (BMI) are known to play a role in the occurrence of this condition. This study was conducted at RSUD Haji Makassar to identify determinant factors influencing the occurrence of preeclampsia in pregnant women. This study used a descriptive-analytical approach with a retrospective design, where secondary data were obtained from medical records of patients diagnosed with preeclampsia during a specific period (year 2024). Analysis was performed on factors influencing the incidence of preeclampsia in pregnant women at RSUD Haji Makassar. Age, parity, BMI, and height significantly influenced the occurrence of preeclampsia. Older age and higher parity increased the risk of preeclampsia. Higher BMI and shorter height were also associated with higher blood pressure, which worsened the condition. However, gravida and weight did not show significant effects. Age, parity, BMI, and height are significant determinants of preeclampsia. Management and prevention of preeclampsia should consider these factors to improve maternal and fetal safety during pregnancy.
References
Adhitya, Y., Sukoco, P., Abimanyu, B., & Andayani, P. (2019). Preeklampsia berat, sindrom HELLP, dan eklampsia terhadap luaran janin (fetal outcome) di RSUD Ulin Banjarmasin. Indonesian Journal of Obstetrics and Science, 2, 143–151. http://dx.doi.org/10.24198/obgynia.v2i2.145
Al-Khataibeh, S. A., Martingano, D. J., & Holland, P. L. (2024). Preeclampsia. StatPearls Publishing.
Al-Tairi, A. N. Q., Isa, Z. M., & Ghazi, H. F. (2017). Risk factors of preeclampsia: A case control study among mothers in Sana’a, Yemen. Journal of Public Health, 25(6), 573–580. https://link.springer.com/article/10.1007/s10389-017-0825-0
American College of Obstetricians and Gynecologists. (2020). Gestational hypertension and preeclampsia: ACOG practice bulletin, number 222. Obstetrics & Gynecology, 135(e237–e260). https://doi.org/10.1097/aog.0000000000003891
Basyiar, A., Mamlukah, M., Iswarawanti, D. N., & Wahyuniar, L. (2021). Faktor risiko yang berhubungan dengan kejadian preeklampsia pada ibu hamil trimester II dan III di Puskesmas Cibeureum Kabupaten Kuningan tahun 2019. Journal of Public Health Innovation, 2(1), 50–60. https://doi.org/10.34305/jphi.v2i1.331
Berhan, Y. (2016). No hypertensive disorder of pregnancy; no preeclampsia-eclampsia; no gestational hypertension; no hellp syndrome. Vascular disorder of pregnancy speaks for all. Ethiopian journal of health sciences, 26(2), 179-188. https://doi.org/10.4314/ejhs.v26i2.12
Boeldt, D. S., & Bird, I. M. (2016). Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia. The Journal of endocrinology, 232(1), R27. https://doi.org/10.1530/joe-16-0340
Chang, K. J., Seow, K. M., & Chen, K. H. (2023). Preeclampsia: Recent advances in predicting, preventing, and managing the maternal and fetal life-threatening condition. International journal of environmental research and public health, 20(4), 2994. https://doi.org/10.3390/ijerph20042994
Dinas Kesehatan Provinsi Sulawesi Selatan. (2021). Profil kesehatan Provinsi Sulawesi Selatan tahun 2021. https://dinkes.sulselprov.go.id/document/Profil%20Kesehatan/
Eva, P. F. (2018). Faktor yang berhubungan dengan kejadian hipertensi pada ibu hamil di wilayah kerja Puskesmas Suli Kabupaten Luwu. Jurnal E-Biomedik, 6(1). https://doi.org/10.35790/ebm.6.1.2018.18797
Grum, T., Seifu, A., Abay, M., Angesom, T., & Tsegay, L. (2017). Determinants of pre-eclampsia/eclampsia among women attending delivery services in selected public hospitals of Addis Ababa, Ethiopia: A case control study. Journal of Pregnancy and Child Health, 1–7. https://doi.org/10.1186/s12884-017-1507-1
Irfa, Z. N. (2021). Gambaran karakteristik ibu hamil risiko tinggi preeklampsia ringan (PER) dan preeklampsia berat (PEB) di Puskesmas Margadana Kota Tegal tahun 2020. Jurnal Kesehatan Reproduksi, 6.
Kementerian Kesehatan Republik Indonesia. (2017). Pedoman nasional pelayanan kedokteran tata laksana komplikasi kehamilan. Jakarta: Kementerian Kesehatan RI.
Khedagi, A. M., & Bello, N. A. (2021). Hypertensive disorders of pregnancy. Cardiology clinics, 39(1), 77-90. https://doi.org/10.1016/j.ccl.2020.09.005
Martadiansyah, A., Qalbi, A., & Santoso, B. (2019). Prevalensi kejadian preeklampsia dengan komplikasi dan faktor risiko yang mempengaruhinya di RSUP Dr. Mohammad Hoesin Palembang (Studi prevalensi tahun 2015, 2016, 2017). Sriwijaya Journal of Medicine, 2, 14–25. https://doi.org/10.32539/sjm.v2i1.30
Martin Jr, J. N., & Morris, R. F. (2019). Preeclampsia-spectrum hypertensive disorders of pregnancy: Gestational hypertension, preeclampsia, eclampsia, chronic hypertension, and HELLP syndrome. In Sex Differences in Cardiovascular Physiology and Pathophysiology (pp. 121-136). Academic Press. http://dx.doi.org/10.1016/B978-0-12-813197-8.00008-7
Mayrink, J., Costa, M. L., & Cecatti, J. G. (2018). Preeclampsia in 2018: revisiting concepts, physiopathology, and prediction. The Scientific World Journal, 2018(1), 6268276. https://doi.org/10.1155/2018/6268276
Peres, G. M., Mariana, M. M., & Cairrão, E. (2018). Pre-eclampsia and eclampsia: An update on the pharmacological treatment applied in Portugal. Pharmaceuticals, 12. https://doi.org/10.3390/jcdd5010003
Perkumpulan Obstetri dan Ginekologi Indonesia (POGI). (2016). PNPK diagnosis dan tatalaksana preeklampsia (pp. 1–48).
Phoswa, W. N., & Khaliq, O. P. (2021). The role of oxidative stress in hypertensive disorders of pregnancy (preeclampsia, gestational hypertension) and metabolic disorder of pregnancy (gestational diabetes mellitus). Oxidative medicine and cellular longevity, 2021(1), 5581570. https://doi.org/10.1155/2021/5581570
Powe, C. E., Levine, R. J., & Karumanchi, S. A. (2011). Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease. Circulation, 123(24), 2856-2869. https://doi.org/10.1161/circulationaha.109.853127
Ramlakhan, K. P., Johnson, M. R., & Roos-Hesselink, J. W. (2020). Pregnancy and cardiovascular disease. Nature Reviews Cardiology, 17(11), 718-731. https://doi.org/10.1038/s41569-020-0390-z
Sanjaya, G. D., Mayulu, N., & Kawengian, S. E. (2018). Faktor Faktor yang Berhubungan dengan Kadar Hemoglobin pada Ibu Hamil di Wilayah Kerja Puskesmas Mopuya. eBiomedik, 6(1). https://doi.org/10.35790/ebm.v6i1.18797
Sello, L., Mappaware, N. A., Aminuddin, A., Asni, S. N., Nilawati, A., & Latief, S. (2020). Pengaruh Pemberian Kurma Ajwa (Phoenix Dactylifera L) Terhadap Hasil Luaran Perinatal Pada Wanita Risiko Preeklampsia. Window of Health: Jurnal Kesehatan, 267-272.
Sharami, S. H., Zendehdel, M., Mirblouk, F., Asgharnia, M., Faraji, R., Fatemeh, S., et al. (2017). Comparison of preeclampsia risk factors regarding to severity with control group. Zahedan Journal of Research in Medical Sciences, 19(1), 5008. https://doi.org/10.1080/10641963.2018.1523919
Sinkey, R. G., Battarbee, A. N., Bello, N. A., Ives, C. W., Oparil, S., & Tita, A. T. (2020). Prevention, diagnosis, and management of hypertensive disorders of pregnancy: a comparison of international guidelines. Current hypertension reports, 22, 1-10. https://doi.org/10.1007/s11906-020-01082-w
Situmorang, T. H., Damantalm, Y., Januarista, A., & Sukri, S. (2016). Faktor-faktor yang berhubungan dengan kejadian PreEklampsia pada Ibu Hamil di Poli KIA RSU Anutapura Palu. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako), 2(1), 34-44. http://dx.doi.org/10.21776/ub.JOIM.2017.001.03.1
Sukma Putri, N. P. W., Wulan, S. W. C., & Denny, Y. P. C. (2020). Faktor-faktor yang berhubungan dengan kejadian preeklampsia di RSUP Sanglah Denpasar. E-Jurnal Medika Udayana, 9(1), 23–25. https://doi.org/10.24843.MU.2020.V9.i1.P05
Wang, A., Rana, S., & Karumanchi, S. A. (2009). Preeclampsia: the role of angiogenic factors in its pathogenesis. Physiology, 24(3), 147-158. https://doi.org/10.1152/physiol.00043.2008
Yuniarti, F., Wijayati, W., & Ivantarina, D. (2018). Analisis perilaku kesehatan dan faktor risiko kejadian preeklampsia pada ibu hamil di Poliklinik Obstetri Ginekologi RSUD Kabupaten Kediri. Journal of Issues in Midwifery, 1–17. http://dx.doi.org/10.21776/ub.JOIM.2017.001.03.1
Copyright (c) 2025 Journal La Medihealtico

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.