Journal La Medihealtico https://newinera.com/index.php/JournalLaMedihealtico <p>International <strong>Journal La </strong><strong>Medihealtico </strong>ISSN 2721-1231 (Online) and 2721-1215 (Print) includes all the areas of research activities in all fields of Medical and Health Care such as Health Care Delivery, Health Care Research, Epidemiology, Medical Care, Nursing, Nursing Education, Neonatal nurse, Home Health Nursing Community and Home care, Information Technology in Nursing, Occupational Health and Safety, Midwifery, Health Care Administration, Hospital Science and Management, Innovations in Patient Care,&nbsp; Public Health, Health Psychology, Social Health, Physical health, Quaternary Care, Secondary Care, Veterinary Nursing, Medical Sciences and Pharmaceutical Sciences, Hospital and Clinical Pharmacy, Pathology, Physiotherapy &amp; Rehabilitation, Ergonomics, Food and Nutrition, Veterinary Medicines.</p> en-US asriwatiamirah@newinera.com (Asriwati Amirah) m.hasibnp@gmail.com (Mujib Hasib) Mon, 15 Jan 2024 00:00:00 +0700 OJS 3.1.2.4 http://blogs.law.harvard.edu/tech/rss 60 The Influence of Sports Habits on Stress Levels of Medical Faculty Students in Surakarta City https://newinera.com/index.php/JournalLaMedihealtico/article/view/1004 <p><em>Stress is a problem in everyday life that is familiar to everyone, especially medical students. Exercise can reduce stress and improve mental health. If exercise is carried out routinely and regularly, it can reduce the activity of the sympathetic nerves and hypothalamic pituitary adrenals. This study aims to determine the effect of exercise habits on stress levels in students at the Faculty of Medicine in Surakarta City. The research used an analytical observational design with a cross sectional approach, with a sample size of 136 respondents consisting of 4 groups/generations. This research uses observation, interviews and questionnaires. Obtaining data from direct interviews with several students who were samples from this research was to identify exercise habits with the IPAQ (International Physical Activity Questionnaire) which were classified into 3, namely light, moderate, high and the level of stress experienced by students using the KPDS (Kessler questionnaire Psychological Distress Scale). The research results were tested using the Spearman rank correlation coefficient test. The results of the research show that there is an influence of exercise habits on the stress levels of Medical Faculty students, with a value of sig. (1-tailed) is 0.009, this value is smaller than the critical limit α = 0.01 (0.009 &lt; 0.01), meaning there is a significant relationship or influence between exercise habits and stress levels. </em></p> Alif Fahran Fadillah, Dodik Nursanto Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1004 Mon, 15 Jan 2024 14:33:00 +0700 The Relationship of Public Mother's Knowledge about Breast Care and the Flowness of Breast Milk in the Watampone Health Center https://newinera.com/index.php/JournalLaMedihealtico/article/view/994 <p><em>Breast care is care that should be done to prepare the breasts so they are in good condition when breastfeeding the baby. In Indonesia, the incidence of mastitis and sore nipples in 2019 was 55% due to errors in breast care, which was found to be 46%. The incidence of postpartum mothers experiencing abscesses in Indonesia in 2019 was 10% due to low knowledge of mothers in breast care. This study aims to determine the relationship between postpartum mothers' knowledge about breast care and smooth breastfeeding at the Watampone health center. This type of research is included in Quantitative research. The type of research used is analytical observational. The population in this study were all postpartum mothers who were at the Watampone Community Health Center UPT and the total sample was 46 people. The results of this study show that of the 46 respondents with good knowledge of breast care and experiencing smooth breastfeeding, there were 10 people (21.7%), while the number of respondents with poor knowledge and experiencing non-fluent breastfeeding was 36 people (78.3%). That there is a significant relationship between knowledge of breast care and smooth breastfeeding in Postpartum mothers at the Watampone Community Health Center UPT. This was proven through Continuity Correction, p-v 549 was obtained, which means there is a relationship between mother's knowledge and smooth breastfeeding at the Watampone health center. In the Lack of Knowledge category, there were 25 people (54.4%). </em></p> Sulfianti Sulfianti, Ismawati Ismawati, Mustar Mustar, Hasnidar Hasnidar, Yulia Arsih Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/994 Mon, 15 Jan 2024 14:55:53 +0700 Birth Length, Diarrheal and Acute Respiratory Infection Risk of Stunting in Toddlers https://newinera.com/index.php/JournalLaMedihealtico/article/view/947 <p><em>Stunting is a linear growth disorder that is indicated by length / age Z score less than minus 2 SD, and categorized as low nutritional status. Short birth length, Infectious diseases such as diarrhea, and Acute Respiratory Infection are indicated to be factors that cause stunting. Objectives The study aimed to analyze the risk factors of short birth length, diarrheal disease, and acute respiratory infection of stunting among children&nbsp; 12-59 months. Methods The study used is quantitative witch a designed case-control study. The subjects were children between 12-59 months. The sample in this study was 120 consisting of 40 stunted and 80 normal. Subjects were chosen by purposive sampling methods. instrument of this research is microtonal, weight scale, and questionnaire. The results of the study were analyzed by chi-square statistics, odds ratio, and logistic regression.&nbsp;The results showed that birth length (PBL) (P = 0.001), diarrhea (P = 0.000), and ARI (P = 0.030) were associated with stunting in children under five. However, after multiple logistic regression analyses, ARI was not significantly associated (P = 0.126). The risk factors for stunting in children under five are diarrhea (OR = 58.134) and short birth length (OR = 9.625).Conclusion:&nbsp;The risk factors for stunting were short birth length and diarrheal disease. </em></p> Musni Musni, St. Malka, Sitti Fatimah, Mutmainnah Mutmainnah Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/947 Sat, 27 Jan 2024 00:00:00 +0700 The Influence of Nurse Behavior on the Completeness of Nursing Care Filling https://newinera.com/index.php/JournalLaMedihealtico/article/view/867 <p><em>Completeness of nursing care is a professional need that needs to be taken into consideration from both an ethical and legal standpoint. This study aimed to analyze the influence of knowledge, attitudes, actions, motivation, workload and the most influential factor on the completeness of nursing care completion at Sufina Aziz Hospital Medan. This is quantitative research using cross-sectional design. The study population was all executive nurses and the sample used 55 executive nurses taken by using total sampling technique. The result of univariate test of good knowledge was 43 people (78.2%), positive attitude was 42 people (76.4%), good action was 7 people (12.7%), strong motivation was 45 people (81.8%), heavy workload was 16 people (29.1%), completeness of nursing care completion with good category was 36 people (65.5%). Chi Square test Sig value with knowledge variable was 0.050 and the attitude value was 0.003 because the p value &lt;0.05, it could be concluded that there was a relationship while the logistic regression test the variable that had the most influence on the completeness of nursing care completion was the attitude variable with a Sig. value of 0.005 (p &lt;0.05).The conclusion shows that the attitude of executive nurses is 22 times at risk of the completeness of nursing care completion at Sufina Aziz Hospital Medan. To ensure that nursing care is provided in line with nursing care standards, it is advised that the executive nurse receive regular monitoring and evaluation for completing nursing care forms completely, properly, and on time.</em></p> Maya Kartika Sari Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/867 Tue, 30 Jan 2024 14:21:52 +0700 The Relationship between Knowledge Level and Attitudes towards Sexually Transmitted Infectious Diseases https://newinera.com/index.php/JournalLaMedihealtico/article/view/1009 <p><em>Sexually Transmitted Infections (STIs) are infectious diseases that can be transmitted from one person to another through sexual contact. Cases of sexually transmitted infections (STIs) continue to increase, the phenomenon of increasing and spreading cases of sexually transmitted infections that occur in high risk groups is very fast, one of those most at risk is teenagers, because teenagers are a transition period from childhood to older age. As they mature, teenagers will become more curious about everything, including sexual matters. To determine the relationship between knowledge and attitudes towards sexually transmitted infections. This type of research uses the approach used is a cross sectional study. The research was conducted at the Indonesian Muslim University, Campus II Jalan Urip Sumoharjo KM.05, Faculty of Medicine, with the research taking place from May 2022 to October 2023. Based on the research results, it shows that the respondents studied in this study tend to have good knowledge about sexually transmitted infections. The respondents studied in this study tended to have a good attitude towards sexually transmitted infections. There was a significant relationship between knowledge and attitudes towards sexually transmitted infections among students of the 2021 Class of Indonesian Muslim University Makassar Medical Education Study Program. </em></p> Anniza Putri Abduh, Dian Amelia Abdi, Zulfiyah Surdam, Lisa Yunita, Sri Wahyuni Gayatri Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1009 Tue, 30 Jan 2024 14:35:01 +0700 Rosacea is More than Just a Red Face: Microbotox's Role in Minimizing Enlarged Facial Pores for a Rosacea Patient https://newinera.com/index.php/JournalLaMedihealtico/article/view/1021 <p><em>Enlarged facial pores are a cosmetic concern and a prominent feature of skin aging that impacts patient quality of life. Microbotox has emerged in multiple studies as a solution for reducing pore size and improving skin texture. A case of 29 years old female with papulopustular rosacea and enlarged skin pores was reported. From the patient's anamnesis, it was found that the patient has been complaining of a reddish patch with pimples on the nose and both cheeks for the past 4 years. The patient has also had enlarged pores on both cheeks for the past 3 years. On dermatologic state there were erythematous macule, erythematous papules and enlarged pores on both of the cheek. Global Flushing Severity Score (GFSS) was 3, Investigator’s Global Assessment (IGA) of Rosacea Severity for papules and pustules is grade 2 and erythema grade 2. Visual Assessment for Pore was 6. Patient received a single session of microbotox. Dermoscopy examination showed linear vessels (telangiectasia), a pustule, and also follicles filled with sebum. Follow up of the patient was done for 6 weeks. Patients reported a decrease in issues such as flushing, papules, pustules, and erythema. A noticeable improvement in pore size was also observed. This action can be repeated every 3 months to maintain clinical improvement and good skin texture. Botulinum toxin exhibits a satisfying level of efficacy and safety in rosacea treatment. A single microbotox session proves to be a safe and effective approach for reducing facial pore size, along with notable improvements in skin texture. </em></p> Adianto Jaya Nagara, Satya Wydya Yenny, Yola Fadhilla, Lilik Norawati, Abraham Arimuko Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1021 Tue, 30 Jan 2024 14:47:50 +0700 Age Estimation via Orocraniofacial Based on Direct Observation and Radiography https://newinera.com/index.php/JournalLaMedihealtico/article/view/1036 <p><em>Determining the estimated age in forensics is very important because it involves legal accountability. The method of determining age estimation can be done by direct measurement of the orocraniofacial bone or by using radiography. This article examines theseveral studies as well as parameters for determining age estimation using orocraniofacial. Search for published articles on Elsevier, Pubmed, Google Scholar, Research Gate, and NCBIon range2007-2021 years. The results show that it is more advisable to determine the age estimate by direct measurement compared to using radiography because it is prone to distortion. </em></p> Andi Eka Asdiana, Ria Puspitawati, Nurtami Soedarsono Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1036 Tue, 30 Jan 2024 15:33:20 +0700 The Effect of Enterobiasis Prevention Education on the Level of Knowledge of Students https://newinera.com/index.php/JournalLaMedihealtico/article/view/1041 <p><em>Enterobiasis is a disease caused by the parasitic worm Enterobius vermicularis. This disease often occurs in children aged 5-14 years. Enterobiasis is a disease that can cause symptoms, one of which is itching in the perianal area. This can cause sleep disorders so that a child's concentration can be disturbed and of course this will affect the child's learning ability, as well as impacting the quality of a generation. This study aims to determine the effect of health education on the level of knowledge of elementary school students in grades 4-6 at SDN Kaliasin 1 Surabaya regarding the prevention of enterobiasis. This research is an observational analytical study with a cross sectional design and uses primary data in the form of a questionnaire. The method used in this research is a quantitative method. The research results showed that before health education, respondents with a good level of knowledge were 24.7%, 48.1% were adequate, and 27.2% were poor, whereas after health education the results obtained were respondents with a good level of knowledge of 64.2%, 24.7% sufficient, and less by 11.1%. Based on the results of the paired Wilcoxon test, the p value was 0.000, which means the p value &lt;0.005, so it can be concluded that there is an influence of health education on the level of knowledge of elementary school students in grades 4-6 at SDN Kaliasin 1 Surabaya on the prevention of enterobiasis.</em></p> Fransisca Dian Nathania Putri, Pramita Anindya Nugraheni, Risma Risma Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1041 Tue, 30 Jan 2024 15:59:59 +0700 Aloin Extract on Histopathological Features of Osteogenesis in Fractures of Rattus Norvegicus Wistar Strains https://newinera.com/index.php/JournalLaMedihealtico/article/view/1049 <p><em>The process of bone repair after trauma or fracture will involve cells, signalling molecules, and processes that have been active during the remodelling process. The new study found that Aloin can promote the expression of osteogenic differentiation regulators, such as Bmp-1 (Bone morphogenetic protein 1) and Runx1 (Runt-related transcription factor 1) in MC3T3–E1 cells, where Runx1 is a transcription factor in osteogenic differentiation—knowing and analyzing aloin extract on the histopathological picture of osteogenesis in Wistar strain rattus norvegicus fractures. This type of research is a laboratory experimental test with a post-test-only control group design. The population number will be divided into four groups, namely positive control group (+), negative control (-), treatment group 1, and treatment group 1, with 14 samples using the Purposive Sampling technique. Univariate data analysis is presented as mean and standard deviation and one-way ANOVA statistical test. Data processing using computerized IBM version 15.0 of the SPSS program. Histopathological picture of osteogenesis in fractures of male rats (Rattus norvegicus) based on osteoblast values at least at K(-), which is 30.64, and K(+), which is 31.90. In the P1 group, the highest average osteoblast value was 39.58, and P1's was 38.14. The osteoclast value is obtained at least at K(-) and 8, and K(+) is 19.01. In the P1 group, the highest average osteoclast value was 16.73, and P1 was 11.70. Aloin extract did not affect the histopathological picture of osteogenesis in fractures of male rats (Rattus norvegicus) with a sig of &gt;0.05.</em></p> Dessy Abdullah, Nadilla Nurrifdah, Budi Yulhasfi Febrianto, Ade Teti Vani, Nadia Purnama Dewi Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1049 Mon, 05 Feb 2024 14:38:48 +0700 Propolis Supplementation Impact on Oxidative Stress in Endometriosis Patients with Levonorgestrel Implant Therapy https://newinera.com/index.php/JournalLaMedihealtico/article/view/1042 <p><em>Diabetes is a persistent metabolic disorder characterized by disruptions in both insulin secretion and action, leading to heightened blood glucose levels (hyperglycemia). Noni fruit, rich in antioxidant compounds like flavonoids and alkaloids, is thought to possess anti-diabetic properties. This study aimed to assess the influence of administering 500 mg/kgBW of noni fruit on the glucose levels of Wistar rats induced with diabetes using 150 mg/kgBW of alloxan. Blood sampling followed a post-test only group method conducted before terminating the mice. The study involved 33 mice divided into three groups: a negative control group, a positive control group induced with diabetes for 3 days, and a treatment group induced with diabetes followed by a 14-day administration of noni fruit extract. The normality test revealed a non-normal distribution with a p value &lt;0.05. Additionally, the Kruskal-Wallis test resulted in a p value &lt;0.05, signifying the impact of noni fruit administration on the blood glucose levels of rats. The Mann-Whitney U test indicated a p value &gt; 0.05 between the positive control group and the treatment group. Despite the absence of a significant difference in glucose levels between the two groups, the study concluded that administering noni fruit at a dose of 500 mg/kgBW could influence the blood glucose levels of mice.</em></p> Citra Krisna Mayasari, Dwirini Retno Gunarti, Lily Indriani Octavia Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1042 Mon, 05 Feb 2024 15:34:14 +0700 The Impact of BMI and Hormonal Contraception on Menstrual Abnormalities: A Cross-Sectional Analysis https://newinera.com/index.php/JournalLaMedihealtico/article/view/1044 <p><em>Hormonal contraception and body mass index (BMI) have been linked to menstrual irregularities, yet the nature of this relationship remains unclear. A cross-sectional study was conducted among0020a sample of 138 women who were using hormonal contraception. Data was collected through self-administered questionnaires. The participants were grouped based on type and duration of hormonal contraception use (combined contraceptives and progestin contraception) and their BMI was calculated based on their height and weight measurements. Menstrual abnormalities were recorded through the participants' self-reported data. Data was analysed using descriptive statistics, chi-square tests, and logistic regression models. Results showed that there was a significant difference in menstrual abnormalities between different types of hormonal contraception p=0.021, OR=2.398,&nbsp; Women who used progestin only contraception had a higher risk of developing menstrual abnormalities than combined contraceptives. There was significance different of duration of use hormonal contraception with menstrual abnormalities p=0.037, OR=2.312 for a long duration (more than 1 years) compared to less than one year. Women with a higher BMI (greater than 25 kg/m2) p=0.038, OR=2.169 had a significant risk of developing menstrual abnormalities. The study concludes that the type and duration of hormonal contraception use and BMI play a significant role in the development of menstrual abnormalities. Women should be informed about the potential risks and benefits of different types of hormonal contraception and the importance of maintaining a healthy BMI. Healthcare providers should consider these factors when making recommendations for hormonal contraception.</em></p> Alexandria Firdaus Al-Farisy Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1044 Mon, 05 Feb 2024 15:48:21 +0700 Analysis of Nurse Role Determinants in Patient Safety Implementation at Royal Prima Marelan Hospital Inpatients https://newinera.com/index.php/JournalLaMedihealtico/article/view/1050 <p><em>Patient safety incidents are still a significant problem at Royal Prima Medan Hospital, where various types of services have risks that threaten patient safety. This study aims to analyze the determinants of nurses' role in implementing patient safety in the Royal Prima Marelan Hospital Inpatient in 2023. This cross-sectional study examines the relationship between independent variables (risk factors) and dependent variables (effects) concerning nurses' roles in patient safety in home inpatient settings. This study included 51 Royal Prima Marelan Inpatient Hospital nurses who were Saturated Sampling. Research variables include the nurse's function, knowledge, attitudes, facilities, and work experience. Univariate, bivariate, and multivariate analyses are used in this research as statistics in determining the frequency distribution or proportion of independent and dependent variables. In implementing patient safety, nurses' roles are primarily good (64.7%), their knowledge is high (60.8%), their attitudes are positive (51.0%), their facilities are reasonable (60, 8%), and their work experience is mostly &gt; three years (64.7%). Based on the analysis of patient safety implementation, knowledge, attitudes, facilities, and work experience all significantly impacted nurses' roles (p=0.008, 0.000, and 0.002, respectively). Hospital nurses have a good attitude toward implementing patient safety, especially if they get good training. Nurse length of service affects patient safety training frequency. More frequent training and better patient safety implementation are associated with longer nursing careers. </em></p> Ricky Suryamin, Sri Lestari Nasution, Tri Suci Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1050 Mon, 05 Feb 2024 16:02:12 +0700 Compare the Effectiveness of a Peel-Off Mask and Sheet-Mask with Green Tea Extract on Dermapen-Treated Wounds on the Back Surface of Female Wistar Rats https://newinera.com/index.php/JournalLaMedihealtico/article/view/1091 <p><em>Microneedling has recently been cited as having high efficacy, safety, and recovery rates post-treatment. This microneedling procedure has shown results that increase patient satisfaction and awareness of doctors who want minimal treatment but still get maximum results for healing uneven skin on the face and acne scarring. The test and analysis of the difference in effectiveness between the use of a peel-off mask and a sheet mask in healing wounds treated with derma pen on the surface of the back skin of female Wistar rats (Rattus norvegicus). This research approach uses experimental quantitative research methods, namely an actual experiment or laboratory experimental design. They used a pre-test – post-test control group design to determine and analyze the differences or comparisons in the effectiveness of using a peel-off mask and a sheet mask for wounds treated with a derma pen on the skin surface. The research subjects were 10 female Wistar rats (Rattus norvegicus). The research procedure was the acclimation of test animals, phytochemical screening, treatment, and observation carried out on mice by administering dermapen wounds. The research data was analyzed using the SPSS program. In this study, Wistar strain white rats (Rattus norvegicus) with peel-off and sheet masks healed their wounds. Dermapen wounds heal after 14 days, as the average rat wound length shows. The peel-off mask group healed 100% on day 13, while the sheet-mask group healed 100% on day 12. Based on this percentage difference, the researchers found that the group with the fastest wound healing used a 12-day green tea sheet mask. </em></p> Henny Hajaratul Aswat, Lenni Dianna Putri, Andri Hidayat Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1091 Mon, 12 Feb 2024 17:32:50 +0700 Comparison of the Effectiveness of Dermapen Using Plasma from Platelets with Dermapen on Pockmarked Skin Surface of Female Wistar Rats (Rattus Norvegicus) https://newinera.com/index.php/JournalLaMedihealtico/article/view/1090 <p><em>Various treatments can cure pockmarks. First, you have to know the cause of the pockmarks and the strength of the pockmarked skin, making it easier to choose the treatment, one of which is dermapen, which uses Plasma from platelets. Test and compare the effectiveness of the derma pen action using Plasma from platelets with the derma pen action on the pockmarked skin surface of female Wistar rats (Rattus Copernicus). This research is a laboratory experiment to compare the effectiveness of the dermapen action using Plasma from platelets with the dermapen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus) using a post-test with control group design or control samples based on treatment groups to analyze the dermapen action using Plasma from platelets with dermapenic action on the surface of rat skin pockmarks. The results showed that the dermapen treatment group with Plasma from platelets at a dose of 10% was more effective in healing cut wounds in white mice than the dermapen treatment group using Plasma from platelets at doses of 2.5% and 5%, respectively. This is because, at a concentration of 10%, blood plasma metabolite compounds from platelets that are applied to wounds already affect the wound. The effect only inhibits microorganisms at small doses, making it less effective in healing wounds. It is recommended that the minimum dose be 10% so that the metabolite compounds in the Plasma from platelets have a healing effect on wounds.</em></p> Endang Dwi Wulansari Roh Nila, Johanna Fransiska Wijaya, Rizki Edmi Edison Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1090 Tue, 20 Feb 2024 15:28:31 +0700 Effectiveness of Oral Providing of Ajwa Date Fruit Extract on Malondialdehyde and Superoxide Dismutase Levels of White Rats Induced by Excessive Physical Activity https://newinera.com/index.php/JournalLaMedihealtico/article/view/1092 <p><em>Natural food ingredients are becoming increasingly popular as a treatment. According to studies and investigations, experts increasingly turn to natural remedies to treat disease, including date fruit extract (Phoenix dactylifera). This study tested the effectiveness of oral date palm fruit extract (Phoenix dactylifera) in reducing blood malondialdehyde levels in white rats (Rattus norvegicus) induced by excessive physical activity and increasing blood levels. Intense physical exercise increases white rat blood superoxide dismutase. This research is a laboratory experimental research or an actual experiment. The research design used a pre-test and post-test with a control group design to analyze the effectiveness of oral administration of date palm (Phoenix dactylifera) extract on the MDA and SOD levels of white rat (Rattus norvegicus) samples induced by excessive physical activity. The results of date fruit extract (Phoenix dactylifera) at 5 ml were more effective at reducing MDA and increasing SOD levels in white mice induced by excessive physical activity than at 3 and 4 ml. The experimental group treated with date fruit extract (Phoenix dactylifera) had lower MDA and higher SOD levels than the group given distilled water. Date fruit extract (Phoenix dactylifera) contains flavonoids and tannins. Some bioactive substances are antioxidants. Antioxidants can assist the body fight free radicals from excessive physical exertion.</em></p> Herlina Jayanti, Muhammad Faridz Syahrian, Zulfikri Mukhtar Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1092 Tue, 20 Feb 2024 15:54:15 +0700 Test of the Effectiveness of Giving Salmon DNA Serum with Virgin Coconut Oil Extract on the Growth of Skin Tissue from Cut Scars on the Skin of Female Wistar Rats (Rattus Norvegicus) https://newinera.com/index.php/JournalLaMedihealtico/article/view/1093 <p><em>Various treatments can cure pockmarks. First, you have to know the cause of the pockmarks and the strength of the pockmarked skin, making it easier to choose the treatment, one of which is dermapen, which uses plasma from platelets. Test and compare the effectiveness of the derma pen action using platelet plasma with the derma pen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus). This research is a laboratory experiment to compare the effectiveness of the dermapen action using plasma from platelets with the dermapen action on the pockmarked skin surface of female Wistar rats (Rattus novergicus) using a post-test with control group design or control samples based on treatment groups to analyze the dermapen action using plasma from platelets with dermapenic action on the surface of rat skin pockmarks. The results showed that the dermapen treatment group with plasma from platelets at a dose of 10% was more effective in healing cut wounds in white mice than the dermapen treatment group using plasma from platelets at doses of 2.5% and 5%. This is because, at a concentration of 10%, blood plasma metabolite compounds from platelets that are applied to wounds already affect the wound. The effect only inhibits microorganisms at small doses, making it less effective in healing wounds. It is recommended that the minimum dose be 10% so that the metabolite compounds in the plasma from platelets have a healing effect on wounds.</em></p> Silvi Apriani, Evelyn Angie, Syamsul Arifin Nasution Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1093 Tue, 20 Feb 2024 16:09:11 +0700 The Effect of Binahong Leaf Extract on Reducing Cholesterol and Histopathological Features in the Liver https://newinera.com/index.php/JournalLaMedihealtico/article/view/1098 <p><em>Being overweight or obese raises your risk of elevated cholesterol, triglycerides, and fatty liver. The liver is crucial to metabolic regulation. Essential to preserve liver health. Maintaining your diet, exercising, and eating antioxidants are all options. Many plants contain antioxidants, like Binahong (Anredera cordifolia). This study examines how Binahong leaf extract reduces cholesterol and improves liver function in high-fat-fed Wistar rats (Rattus norvegicus) and their liver histology. An actual experiment or laboratory experimental study is quantitative. 24 Wistar rats were sampled. Binahong leaf extract was the independent variable, cholesterol levels liver histological features were the dependent variable, and a high-fat diet was the precondition. The test animals were put into four groups: control, groups 2, 3, and 4 with Binahong leaf extract at 30mg/BW, 50mg/BW, and 70mg/BW. SPSS normality, homogeneity, and ANOVA tests. If p &gt; 0.05, research results are generally distributed with 0.200 significance. Significant homogeneity was 0.176 &gt; 0.05. Effective One-Way ANOVA test results (0.000 or &lt;0.05). Post Hoc LSD test analysis yielded important values of 0.000.0001 and 0.024 &lt; 0.05. The phytochemical test found flavonoids, alkaloids, saponins, steroids, and tannins in Binahong leaf extract. Binahong leaf extract at 70 mg/BW reduced cholesterol, body weight, and LDL in hypercholesterolemic male white mice best. The study found that Binahong leaf extract's secondary metabolites—flavonoids, alkaloids, saponins, steroids, and tannins—reduce cholesterol, LDL, and body weight in Wistar strain white rats (Rattus Norvegicus) with hypercholesterolemia.</em></p> Risca Trisnawati, Michelle Hendriani Djuang, Johnson Hutapea Copyright (c) 2024 Journal La Medihealtico http://creativecommons.org/licenses/by-sa/4.0/ https://newinera.com/index.php/JournalLaMedihealtico/article/view/1098 Tue, 20 Feb 2024 16:18:30 +0700