Literature Review: Effects of Turmeric for Reducing Lipid Profiles

  • Muh Alif Fadillah Doctor of Medicine Study Program, Faculty of Medicine, Universitas Muslim Indonesia
  • Rezky Putri Indarwati Clinical Supervising Doctor of Public Health Science Department, Universitas Muslim Indonesia
  • Muh Jabal Nur Supervising Doctor of Internal Medicine Specialist Clinic, Rumah Sakit Hermina
Keywords: Effects of Turmeric, Lipid Profile, Curcumin, Literature Review

Abstract

This literature review is a collection of several journals which aims to determine the effect of turmeric (Curcuma longa) on reducing lipid profiles, with emphasis on cholesterol and triglyceride levels. Turmeric is a daily food ingredient that is easy to find and has many good effects on the body, one of which is anti-inflammatory and anti-hypercholesterolemia. Hypercholesterolemia is a condition where the total cholesterol level in the body exceeds normal and can increase the risk of atherosclerosis. Curcumin is one of the active compounds in turmeric which has the function of reducing total cholesterol, LDL cholesterol, triglycerides which cause atherosclerosis and curcumin also increases the production of HDL cholesterol which helps protect against excess cholesterol accumulation which can cause heart and blood vessel disease. Based on several literature reviews, it is reported that the effectiveness of reducing cholesterol levels starts from a dose of 1000 mg - 1500 mg/day. The main aim of this research is to determine the effectiveness and safety of using turmeric as a supplement in reducing lipid profile levels in humans. Through this research, it is hoped that it can provide information regarding the effectiveness of turmeric as an effective additional therapy in managing lipid profiles.

References

Azis, A. (2019). Kunyit (Curcuma domestica Val) Sebagai Obat Antipiretik. Jurnal Ilmu Kedokteran dan Kesehatan, 6(2), 116–120.

Budiarto, A. A., Wibowo, A. P., Putri, S. A., Shabrina, N. N., Ngestiningsih, D., & Tjahjono, K. (2017). Pengaruh pemberian ekstrak rimpang temulawak (Curcuma Xanthorrhiza Roxb.) dan jintan hitam (Nigella Sativa) terhadap profil lipid tikus Sprague Dawley dislipidemia. Majalah Kedokteran Bandung, 49(1), 8-14.

Dehzad, M. J., Ghalandari, H., Amini, M. R., & Askarpour, M. (2023). Effects of curcumin/turmeric supplementation on lipid profile: A GRADE-assessed systematic review and dose–response meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 75, 102955.

Dewi, S. H. C., Wariyah, C., & Astuti, N. (2021). Efek Hipoglikemik dan Hipolipidemik Dendeng Daging Itik Curing dengan Ekstrak Kurkumin Kunyit pada Tikus Wistar. Livestock and Animal Research, 19(3), 301. Retrieved from https://jurnal.uns.ac.id/lar/article/view/48708

Diantari, N. K., & Astuti, K. W. (2023). Potensi Ekstrak Rimpang Jahe Merah (Zingiber officinale Rosc. var rubrum) Sebagai Nutraceutical. Prosiding Workshop dan Seminar Nasional Farmasi, 2, 631–642. https://doi.org/10.15395/mkb.v49n1.982

Estancia, K., Isroli, I., & Nurwantoro, N. (2012). Pengaruh Pemberian Ekstrak Kunyit (Curcuma Domestica) terhadap Kadar Air, Protein dan Lemak Daging Ayam Broiler. Animal Agriculture Journal, 1(2), 31–39.

Fahrumnisa, A. R. (2019). Ekstrak Kunyit (Curcuma longa) sebagai Tatalaksana Sindrom Polikistik Ovarium. Jurnal Ilmiah Kesehatan Sandi Husada, 8(2), 115–120. https://doi.org/10.35816/jiskh.v10i2.125

Jarhahzadeh, M., Alavinejad, P., Farsi, F., Husain, D., & Rezazadeh, A. (2021). The effect of turmeric on lipid profile, malondialdehyde, liver echogenicity and enzymes among patients with nonalcoholic fatty liver disease: a randomized double blind clinical trial. Diabetology & Metabolic Syndrome, 13(1), 112. https://doi.org/10.1186/s13098-021-00731-7

Midah, Z., Indarwati Abdullah, R. P., & Fajriansyah, F. (2022). Pkm Sosialisasi Bahaya Hiperkolesterolemia pada Tubuh dan Pemeriksaan Kadar Kolesterol di Desa Paddingin Kabupaten Takalar. Jurnal Pengabdian Kedokteran Indonesia, 3(1), 14–20. https://doi.org/10.33096/jpki.v3i1.176

Nuralifah, N., Wahyuni, W., Parawansah, P., & Dwi Shintia, U. (2019). Uji Aktivitas Antihiperlipidemia Ekstrak Etanol Daun Notika (Arcboldiodendron calosericeum Kobuski) Terhadap Kadar Kolesterol Total Tikus (Rattus norvegicus) Jantan Galur Wistar. Journal Syifa Sciences and Clinical Research, 2(1), 1–10. https://doi.org/10.37311/jsscr.v2i1.2704

Nuryanti, N., Suprihatin, T., & Saraswati, T. R. (2022). Peran Serbuk Kunyit dan Kurkumin Terhadap Diferensial Leukosit Tikus Putih (Rattus norvegicus) yang Diberi Pakan Hiperlipid. Buletin Anatomi dan Fisiologi, 7(1), 42–50. https://doi.org/10.14710/baf.7.1.2022.42-50

Patonah, Sulaeman, A., & Pambudi, D. R. (2022). Atherorotektif Efek Pegagan (Centella Asiatica L.) dan Kunyit (Curcuma Longa L.) dalam Sediaan Jus pada Model Hewan Hiperlipidemia. Jurnal Ilmiah Manuntung, 8(1), 63–70. https://doi.org/10.51352/jim.v8i1.488

Pujiastuti, S. E., Hadisaputro, S., & Pujiastuti, S. E. (2021). Efektifitas Pemberian Nanopartikel Kunyit Terhadap Tekanan Darah Dan Profil Lipid Pada Pasien Hipertensi Dengan Hiperkoletrolemia.

Puteri, F. D. (2020). Efek Kurkumin Pada Kunyit (Curcuma longa) sebagai Pengobatan Kanker Lambung. Jurnal Ilmiah Kesehatan Sandi Husada, 12(2), 860–864. Retrieved from https://akper-sandikarsa.e-journal.id/JIKSH/article/view/426

Qin, S., Huang, L., Gong, J., Shen, S., Huang, J., Ren, H., & Hu, H. (2017). Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: a meta-analysis of randomized controlled trials. Nutrition Journal, 16(1), 68.

Rahmah, A. H. A. (2019). Efektivitas Rimpang Kunyit (Curcuma Domestica) Terhadap Penurunan Risiko Aterosklerosis. PREVENTIF: Jurnal Kesehatan Masyarakat, 10(2), 113–120.

Safitri, S., & Gustina, G. (2022). Edukasi Kunyit Asam Pereda Dismenorea. Jurnal Abdimas Kesehatan (JAK), 4(2), 178.

Sahara, L. I., & Adelina, R. (2021). Analisis Asupan Lemak terhadap Profil Lemak Darah Berkaitan dengan Kejadian Penyakit Jantung Koroner (Pjk) di Indonesia: Studi Literatur. Jurnal Pangan Kesehatan dan Gizi Universitas Binawan, 1(2), 48–60. https://doi.org/10.54771/jakagi.v1i2.152

Syamsu, R. F., Thahira, Y. M., Nasruddin, H., Dahlia, D., Indarwati, R. P., Palloge, S. A., Nurdin, A. Z., et al. (2024). The Effectiveness of Olive Oil in Preventing Atherosclerosis: A Literature Review. Poltekita: Jurnal Ilmu Kesehatan, 17(4), 1305–1310.

Thendry, A., Loho, L. L., & Lintong, P. M. (2015). Pengaruh Pemberian Ekstrak Kunyit Terhadap Gambaran Hispotalogi Aotar Tikus Witar Hiperlipidemia. eBiomedik, 3(1), 199–204.

Uda’a, R., Dahliah, Wiriansya, E. P., Rahmawati, & Indarwati, R. P. (2023). Pengaruh Terapi Bekam Terhadap Kadar Kolesterol Total Pada Pasien Hiperkolesterolemia di Klinik Hamdalah Makassar. Fakumi Medical Journal: Jurnal Mahasiswa Kedokteran, 3(8), 563–572.

Widiyanto, B., Intan, N., Thoyibah, N. K., Sudjudi, Y., & Faza, A. S. (2023). The Combination of Soursop and Turmeric Leaf Extracts Improves Lipid Profiles in Metabolic Syndrome Model Mice. Jurnal Ilmiah Kesehatan (JIKA), 5(1), 113–120. https://doi.org/10.36590/jika.v5i1.413

Winarti, R., Saraswati, T. R., & Tana, S. (2021). Pengaruh Serbuk Kunyit dan Kurkumin terhadap Kualitas Spermatozoa Tikus Putih (Rattus norvegicus) yang Diberi Pakan Hiperlipid. Jurnal Akademika Biologi, 10(1), 24–31.

Yusuf, H. Y. (2023). Efektivitas Penggunaan Kurkumin terhadap Peningkatan Sistem Imun Tubuh. Dharmakarya, 12(1), 40.

Published
2024-06-12
How to Cite
Fadillah, M. A., Indarwati, R. P., & Nur, M. J. (2024). Literature Review: Effects of Turmeric for Reducing Lipid Profiles . Journal La Medihealtico, 5(2), 445-454. https://doi.org/10.37899/journallamedihealtico.v5i2.1273