The Correlation between Leukopenia and the Severity of Dengue Hemorrhagic Fever in Pediatric Patients

Angelina Mulyadi; Judya Sukmana; Pramita Anindya; Suliman Purwoko

doi:10.37899/journallamedihealtico.v5i1.1079

Angelina Mulyadi Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia
Judya Sukmana Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia
Pramita Anindya Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia
Suliman Purwoko Faculty of Medicine, Hang Tuah University, Surabaya, Indonesia

DOI: https://doi.org/10.37899/journallamedihealtico.v5i1.1079

Keywords: DHF, DHF grade, Leukopenia

Abstract

The aim of this study is to investigate the correlation between leukopenia and the severity of DHF in pediatric patients treated at RSPAL dr. Ramelan Surabaya from January 2021 to December 2022. This analytical observational study employed a cross-sectional design, involving 126 patient records from RSPAL dr. Ramelan Surabaya during the specified period. The sample selection was done using purposive sampling. The variables under investigation were leukopenia on days 2 to 5 and the DHF grade in patients aged 5 to 14 years. The statistical correlation test, Kendall's tau-b, indicated that there is no significant correlation between leukopenia and the severity of DHF in pediatric patients, with a p-value of 0.340, meaning p > α (with α = 0.05). The data revealed that out of the patients, 88 (69.8%) had Grade I, 16 (12.7%) had Grade II, 19 (15.1%) had Grade III, and 3 (2.4%) had Grade IV. Leukopenia occurred in 49 (73.1%) Grade I patients, 9 (13.4%) Grade II patients, 7 (10.4%) Grade III patients, and 2 (3%) Grade IV patients. In conclusion, this study found no significant correlation between leukopenia and the severity of DHF in pediatric patients treated at RSPAL dr. Ramelan Surabaya from January 2021 to December 2022.

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