Physiological Therapeutic Protective Function of Thymoquinone on Mice Fertility

  • Jabbar Jassim Hamady Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Wasit, Wasit, Iraq
  • Mohammed S. A. Hayyawi Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Wasit, Wasit, Iraq
Keywords: Thymoquinone, Fertility, Environmental conditions, Reproductive system, Iraq

Abstract

The experiment was conducted in the college of veterinary medicine at the University of Wasit to determine the role of therapeutic administration of thymoquinone on male mice fertility as a muddle for mammalian. Through the study, 16 mice have been separated into two groups equally: the control group administered distal water and kept in 25±2ºC, and the thymoquinone groups kept at 25±2ºC and administered thymoquinone 25 mg/kg b.w. for 2 weeks. After the end of the drenched period on the last day of the experiment, mice were not drenched for 24 hours, and ketamine 100 mg/kg and xylazine 10 mg/kg were administered to the scarified mice. 100 mg of testis samples were taken from the testis of all groups and kept at liquid nitrogen for PCR to determine the effects of stress through significant differentiation of HSP70 protein in testis tissue. The experiment showed a highly significant effect of the thymoquinone group (25 mg/kg b.w.) when compared with the control group.

Published
2024-11-14
How to Cite
Hamady, J. J., & Hayyawi, M. S. A. (2024). Physiological Therapeutic Protective Function of Thymoquinone on Mice Fertility. Journal La Lifesci, 5(5), 521-528. https://doi.org/10.37899/journallalifesci.v5i5.1695