The Discovery and History of Animal and Human Physiology

  • Guirad Oth Department of Science and Technology, University of the Phiippines, Phiippines
  • Yrick John Department of Science and Technology, University of the Phiippines, Phiippines
Keywords: Nucleus, DNA, Endoplasmic


This study discusses Nucleus, history of the discovery of the cell nucleus Structure and parts of the cell nucleus. All of them is the phisiology of animal and human. The cell nucleus (nucleus) can be defined as an organelle found in eukaryotic cells. Nucleoplasm The nucleoplasm is the liquid that is in the nucleus which is thick and transparent. The cell nucleus has many genes from DNA which are arranged and form structures called chromosomes. The endoplasmic reticulum consists of tubules, vesicles and flattened pockets that occupy the cytoplasmic space. The endoplasmic reticulum is a part of the cell that consists of a membrane system, which has a structure that resembles a multi-layered sac. These sacs are called cisternae.


Bechtel, W. (2006). Discovering cell mechanisms: The creation of modern cell biology. Cambridge University Press.

Calogero, S., Grassi, F., Aguzzi, A., Voigtländer, T., Ferrier, P., Ferrari, S., & Bianchi, M. E. (1999). The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice. Nature genetics, 22(3), 276-280.

Cremer, T., Kurz, A., Zirbel, R., Dietzel, S., Rinke, B., Schröck, E., & Lichter, P. (1993). Role of chromosome territories in the functional compartmentalization of the cell nucleus. In Cold Spring Harbor Symposia on Quantitative Biology (Vol. 58, pp. 777-792). Cold Spring Harbor Laboratory Press.

rhMcCue, A. D., Cresti, M., Feijó, J. A., & Slotkin, R. K. (2011). Cytoplasmic connection of sperm cells to the pollen vegetative cell nucleus: potential roles of the male germ unit revisited. Journal of experimental botany, 62(5), 1621-1631.

Moga, M. M., Saper, C. B., & Gray, T. S. (1989). Bed nucleus of the stria terminalis: cytoarchitecture, immunohistochemistry, and projection to the parabrachial nucleus in the rat. Journal of Comparative Neurology, 283(3), 315-332.

Pierre, V., Martinez, G., Coutton, C., Delaroche, J., Yassine, S., Novella, C., & Arnoult, C. (2012). Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus. Development, 139(16), 2955-2965.

Zalensky, A. O., Allen, M. J., Kobayashi, A., Zalenskaya, I. A., Balhorn, R., & Bradbury, E. M. (1995). Well-defined genome architecture in the human sperm nucleus. Chromosoma, 103(9), 577-590.

Zanta, M. A., Belguise-Valladier, P., & Behr, J. P. (1999). Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proceedings of the National Academy of Sciences, 96(1), 91-96.

Zhang, R., Mehla, R., & Chauhan, A. (2010). Perturbation of host nuclear membrane component RanBP2 impairs the nuclear import of human immunodeficiency virus-1 preintegration complex (DNA). PloS one, 5(12), e15620.

How to Cite
Oth, G., & John, Y. (2020). The Discovery and History of Animal and Human Physiology. Journal La Lifesci, 1(6), 19-27.